MCQ
An amino acid may be represented by general formula $\begin{matrix}
   R\,\,\,\,\,\,\,\,  \\
   |\,\,\,\,\,\,\,\,  \\
   {{H}_{2}}N-CH-COOH  \\
\end{matrix}$ If $R = -CH_2C_6H_5$ then it is phenylalanine $(Phe)$ and if $R = CH_3$ then it is alanine $(Ala)$. Find the sequence of reagents from those given below to synthesize $Phe- Ala$

$(1)$ $\begin{matrix}
   C{{H}_{3}}  \\
   |\,\,\,\,\,\,  \\
   ZNH\,C\,HC{{O}_{2}}H  \\
\end{matrix}$                             $(2)$ $\begin{matrix}
   C{{H}_{3}}\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,  \\
   |\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,  \\
   {{H}_{2}}N\,C\,HC{{O}_{2}}C{{H}_{2}}{{C}_{6}}{{H}_{5}}  \\
\end{matrix}$

$(3)$ $\begin{matrix}
   \,\,\,\,\,\,\,\,\,\,\,\,C{{H}_{3}}{{C}_{6}}{{H}_{5}}  \\
   |\,\,\,\,\,  \\
   ZNH\,C\,HC{{O}_{2}}H  \\
\end{matrix}$                $(4)$ $\begin{matrix}
   C{{H}_{2}}{{C}_{6}}{{H}_{5}}\,\,\,\,\,  \\
   |\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,\,  \\
   {{H}_{2}}N\,CHC{{O}_{2}}C{{H}_{2}}{{C}_{6}}{{H}_{5}}  \\
\end{matrix}$

  • A
    $1$ and $2$
  • $1$ and $4$
  • C
    $2$ and $3$
  • D
    $3$ and $4$

Answer

Correct option: B.
$1$ and $4$
b
$(b)$

$NH _2$ Group from $(2)$ reacts with $COOH$ from $(3)$ to form phe- ala Ans is $(C)$

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