MCQ
Chargaff’s rules are applicable to:
  • Single stranded $\text{RNA.}$
  • B
    Single stranded $\text{DNA}$ and $\text{RNA.}$
  • C
    Single stranded $\text{DNA.}$
  • D
    Double stranded $\text{DNA.}$

Answer

Correct option: A.
Single stranded $\text{RNA.}$
Chargaff's rules state that $\text{DNA}$ from any cell of any organisms should have a $1 : 1$ ratio of pyrimidine and purine bases and, more specifically, that the amount of guanine should be equal to cytosine and the amount of adenine should be equal to thymine. This pattern is found in both strands of the $\text{DNA.}$
Since single stranded $\text{RNA}$ and $\text{DNA}$ do not have complementary bases, Chargaff's rule is not applicable to them.

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