Corpus luteum in pregnancy has a long life. However, if fertilisation does not take place it remains active only for 10 – 12 days. Why?
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This is because of a neural signal given by the maternal endometrium to its hypothalamus in presence of a zygote to sustain the gonadotropin (LH) secretion, so as to maintain the corpus luteum as long as the embryo remains there. In the absence of a zygote, therefore, the corpus luteum degenerates
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