Question
Describe Mendelian disorders and mention its two types giving suitable examples.

Answer

Mendelian disorders are determined by mutation in the single gene and transmitted to the offspring as per Mendelian principles. The pattern of inheritance of such Mendelian disorders can be traced in a family by Pedigree analysis.
The Mendelian disorders are of two main types:
  1. Gene Mutations in sex chromosomes. Examples: Sickle-cell anaemia and Phenylketonuria.
  2. Gene Mutations in sex chromosomes.
Example: Haemophilia.

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