Question
Differentiate between conformation and configuration in open chain molecules by giving one example each.
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Answer
| Conformations | Configuration |
| These spatial arrangement are obtained by rotation of groups around sigma bond. The interconversion of these isomers does not require breaking of bonds. Ex. Staggerd and Eclipsed conformation of ethane. | Configurational isomers are due to certain types of rigidity within the molecules and these isomers can be interconverted only by breaking and re making of covalent bonds and not simply by rotation. Ex. D-Glyceraldehyde and L-Glyceraldehyde configurations. |
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