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Molecular Basis of Inheritance — BIOLOGY STD 12 Science — Question

Rajasthan BoardEnglish MediumSTD 12 ScienceBIOLOGYMolecular Basis of Inheritance2 Marks
Question
Differentiate between leading strand and lagging strand.
✓

Answer

S.No.
Leading strand
Lagging strand
1.
It is a replicated strand of DNA which grows continuously without any gap.
The lagging strand is a replicated strand of DNA which is formed in short segments called discontinuous.
2.
It does not require DNA ligase for its growth.
DNA ligase is required for joining okazaki fragments.
3.
The direction of growth of a leading strand is 5' → 3'.
The direction of the lagging strand is 3' → 5'.
4.
Only a single RNA primer is required.
Starting of each okazaki fragment requires a new RNA.
5.
Its template opens in 3' → 5' direction.
Its template opens in 5' → 3' direction
6.
Formation of leading strand begins immediately at the beginning of replication
Formation of lagging strand begins a bit later than that of leading strand.

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