Question
Differentiate between leading strand and lagging strand.

Answer

S. No.
Leading Strand
Lagging Strand
1.
It is a replicated strand of DNA which grows continuously without any gap.
Lagging strand is a replicated strand of DNA which is formed in short segments called Okazaki fragments. Its growth is discontinuous.
2.
It does not require DNA ligase for its growth.
DNA-ligase is required for joining Okazaki fragments.

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