The Fundamental Unit of Life — Science STD 9 — Question

The major differences between rough and smooth endoplasmic reticulum are:

Smooth Endoplasmic Reticulum	Rough Endoplasmic Reticulum
SER has no ribosomal particles on the surface, hence look smooth.	RER has particles of ribosome on the surface, therefore are rough in texture.
It helps in manufacturing of lipids and fat molecules.	They are the sites of protein synthesis.

Endoplasmic reticulum synthesises lipids (smooth endoplasmic reticulum) and proteins (rough endoplasmic reticulum) which are responsible for formation of membrane. Thus, they help in membrane biogenesis.