Question
Differentiate between rough and smooth endoplasmic reticulum. How is the endoplasmic reticulum important for membrane biogenesis?

Answer

Rough Endoplasmic ReticulumSmooth Endoplasmic Reticulum
Ribosomes are present on the surface.Ribosomes are absent.
Involved in the synthesis of protein.Involved in the synthesis of fat and lipid.
ER makes lipid and protein which are the two important constituents of the plasma membrane. The biogenesis of the plasma membrane is dependent on the endoplasmic reticulum.

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