Question
Differentiate between Rough Endoplasmic Reticulum (RER) and Smooth Endoplasmic Reticulum (SER).

Answer

Differences between SER and RER are:
 
SER
RER
(i)
It does not bear ribosomes over the surface of its membrane.
It possess ribosomes atteched to its membrane.
(ii)
Its main function is synthesis of lipids.
Its main function is synthesis of proteins.
(iii)
Formed of vesicles and tubules.
Formed of cisternae and few tubules.
(iv)
It is usually found in periphery.
It is found deep inside the cytoplasm.
(v)
It may develop from RER.
It may develop from nuclear envelope.

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