→In higher lineages, memory-based acquired immunity is based on the ability to distinguish between self and non self (pathogens), which can be understood from two principles:
→Higher order lineages can differentiate into individual cells as well as individual organisms.
→Much of experimental immunology runs on this aspect.
→Sometimes due to genetic or other unknown reasons, the body attacks its own cells, resulting in damage to the body, which is called an auto- immune disease.
→Example :
→Gout (rheumatoid arthritis).