Question
Explain innate immunity in detail

Answer

Innate immunity is non-specific immunity, which is present at the time of birth.
1) Physical barrier :
Our skin is the main physical barrier that prevents the entry of microorganisms.
Mucous membrane lining the respiratory tract, gastrointestinal tract and urinary tract also helps to prevent germs from entering the body.
2) Physiological barrier:
Acid in the stomach, saliva in the mouth, tears in the eyes etc. inhibit the growth of pathogens.
3) Cellular Barrier :
Some white blood cells [WBCs] in our body, such as polymorphonuclear leukocytes and natural killer cells, a type of lymphoid cell in the blood, can feed on and destroy microbes.
(4)Cytokine barrier:
Virus-infected cells secrete proteins called interferons, which protect other uninfected cells from virus infection.

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Describe the process of DNA Fingerprinting in detail.
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Growth of a population with time shows specific and predictable patterns. Two types of growth pattern of population are exponential and logistic growth. When resources in the habitat are unlimited each species has the ability to realise fully its innate potential to grow in number. Then the population grows in exponential fashion. When the resources are limited growth curve shows an initial slow rate and then it accelerates and finally slows giving the growth curve which is sigmoid.

  1. Which of the following statement is incorrect?
  1. Exponential growth occurs in organism such as lemmings.
  2. Logistic growth is more realistic.
  3. Exponential growth has two phases lag and log.
  4. ln logistic growth, population passes well beyond the carrying capacity of ecosystem.
  1. Which of the following equations correctly represents the exponential population growth curve?
  1. $\text{dN}/\text{dt}=\text{rN}$

  2. $\text{dN}/\text{dt}=\text{rN}\Big(\frac{\text{K-N}}{\text{K}}\Big)$

  3. $\text{N}_\text{t}=\text{N}_\text{o}\text{e}^\text{rt}$

  4. Both (a) and (c).
  1. Which of the following equations correctly represents Verhulst-Pearl logistic growth?
  1. $\text{dN}/\text{dt}=\text{rN}\Big(\frac{\text{K-N}}{\text{K}}\Big)$

  2. $\text{dN}/\text{dt}=\frac{\text{rN}}{\text{K}}$

  3. $\text{dN}/\text{dt}=\frac{\text{N}(\text{K}-\text{N})}{\text{K}}$

  4. $\text{dN}/\text{dt}=\frac{\text{r}(\text{K}-\text{N})}{\text{K}}$

  1. The population growth is generally described by the following equation:

$\frac{\text{dN}}{\text{dt}}=\text{rN}\Big(\frac{\text{K}-\text{N}}{\text{K}}\Big)$

What does 'r' represent in the given equation?

  1. Population density at time 't'.
  2. Intrinsic rate of natural increase.
  3. Carrying capacity.
  4. The base of natural logarithm.
  1. Study the population growth curves (A and B) in the given graph and select the incorrect option.

  1. Curve 'A: shows exponential growth, represented by equation $\frac{\text{dN}}{\text{dt}}=\text{rN}$.

  2. Curve 'B' shows logistic growth, represented by equation $\frac{\text{dN}}{\text{dt}}=\text{rN}\Big(\frac{\text{K}-\text{N}}{\text{K}}\Big)$

  3. Exponential growth curve is considered as more realistic than the logistic growth curve.
  4. Curve 'A' can also be represented by equation $\text{N}_\text{t}=\text{N}_\text{o}\text{e}^\text{rt}$.

Read the following and answer any four questions from (i) to (v) given below:
DNA fingerprinting is a technique of determining nucleotide sequences of certain areas of DNA which are unique to each individual. Each person has a unique DNA fingerprint. Each fingerprint is the same for every cell, tissue and organ of a person. DNA fingerprinting is the basis of paternity testing in case of disputes.
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  1. DNA profiting
  2. DNA fingerprinting
  3. RFLP
  4. Both (a) and (b).
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  1. Blood
  2. Hair root cells
  3. Semen
  4. All of these
  1. During DNA fingerprinting, the radioactive probes.
  1. Hybridise with DNA sample to form double stranded structure
  2. Egrade the DNA
  3. Create positive charge on DNA
  4. Cut the DNA sample at various sites.
  1. In India, DNA fingerprinting technique was developed by?
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  2. Alec Jeffreys
  3. Dr. Khorana
  4. None of these.
  1. Which of the following is true about DNA fingerprinting?
  1. VNTR is used as probe.
  2. DNA samples are loaded on agarose gel electrophoresis.
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Given below is the pattern of temperature in a person suffering from a non-viral disease transmitted by mosquitoes. Study the graph and answer the questions that follow:
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C. How is this infection transmitted to humans?
OR
D. Which stages of the life cycle of this pathogen are completed in the mosquito's gut?
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The given graphs show fluctuations in blood sugar of person X and Y during a 24 hour time period.

Based on the above information, answer the following questions.

  1. Which of the following holds true for person X?
  1. Person X is suffering from type I diabetes.
  2. Person X shows severe insulin deficiency and beta cell depletion.
  3. Person X is normal and shows good control of blood sugar level.
  4. Person X is subjected to excessive urination and abnormal thrust.
  1. The given graph indicates that person Y is suffering from.
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  2. Hypertension
  3. Atherosclerosis
  4. Rheumatic heart disease.
  1. Which of the following conditions are common in person Y?
  1. Excretion of glucose in urine and excessive urination.
  2. Polydipsia and mild beta cell depletion.
  3. Progressive erosion of articular cartilage at synovial joint.
  4. Both (a) and (b).
  1. A person suffering from diabetes mellitus becomes weak because.
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  2. Degradation of fat increases production of toxic ketone bodies.
  3. Cells utilise proteins for obtaining energy
  4. All of these.
  1. Assertion: Type I diabetes involves failure of insulin to facilitate the movement of glucose into cells.

Reason: Type II diabetes is caused by failure of beta cells to produce adequate amount of insulin due to beta cell depletion.

  1. Both assertion and reason are true, and reason is the correct explanation of assertion.
  2. Both assertion and reason are true, but reason is not the correct explanation of assertion.
  3. Assertion is true, but reason is false.
  4. Both assertion and reason are false.
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Riya studies in 11 standard in a government school. She belongs to a backward family and her parents did not get her properly vaccinated according to immunisation programme. Once while playing in school playground she fell down due to weakness and developed high fever, headache and stiffness in her neck. identify the illness she could be suffering from and answer the following questions.

  1. The microbe responsible for Riya's illness could be.
  1. Vibrio cholerae
  2. Enterovirus
  3. Plasmodium
  4. Mycobacteriurn.
  1. Which vaccine, if administered earlier, would have saved Riya from the illness she unfortunately contracted?
  1. Salk vaccine
  2. MMR vaccine
  3. BCG vaccine
  4. Varicella vaccine
  1. The disease that Riya has contracted spreads through.
  1. Bite of an infected mosquito
  2. Bite of an infected dog
  3. Faecal oral route
  4. Direct contact with the infected person.
  1. Riya can spread her illness to other children through.
  1. Her faeces
  2. Direct contact
  3. Coughing and sneezing in open
  4. Vectors.
  1. Assertion: Polio produces inflammation of the nervous system.

Reason : Stiffness of the neck, paralysis of particular skeletal muscle, is an important symptom of polio.

  1. Both assertion and reason are true, and reason is the correct explanation of assertion.
  2. Both assertion and reason are true, but reason is not the correct explanation of assertion.
  3. Assertion is true, but reason is false.
  4. Both assertion and reason are false.
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The process of translation requires transfer of genetic information from a polymer of nucleotides to synthesise a polymer of amino acids. The relationship between the sequence of amino acids in a polypeptide and nucleotide sequence of DNA or mRNA is called genetic code. George Gamow suggested that in order to code for all the 20 amino acids, code should be made up of three nucleotides.

  1. What is a codon?
  1. A length of DNA which codes for a particular protein.
  2. A part of the tRNA molecule to which a specific amino acid is attached.
  3. A part of the tRNA molecule which recognises the triplet code on the messenger RNA.
  4. A part of the messenger RNA molecule that has a sequence of bases coding for an amino acid.
  1. Three consecutive bases in the DNA molecule provide the code for each amino acid in a protein molecule. What is the maximum number of different triplets that could occurs?
  1. 16
  2. 20
  3. 24
  4. 64
  1. Listed below are some amino acids and their corresponding mRNA triplets.
Amino acid
mRNA triplet
Phenylalanine
UUU
Lysine
AAG
Arginine
CGA
Alanine
GCA
Which DNA sequence would be needed to produce the following polypeptide sequence? Alanine-Arginine-Lysine-Phenylalanine

  1. $\text{CGT}\ \ \ \text{GCT}\ \ \ \text{TTC}\ \ \ \text{AAA}$

  2. $\text{CGT}\ \ \ \text{GCT}\ \ \ \text{TTC}\ \ \ \text{TTT}$

  3. $\text{CGU}\ \ \ \text{GCU}\ \ \ \text{UUC}\ \ \ \text{AAA}$

  4. $\text{CGU}\ \ \ \text{GCU}\ \ \ \text{UUC}\ \ \ \text{TTT}$

  1. Identify the non-sense codons among the following.
  1. AUG
  2. GUG
  3. UAA
  4. UGG
  1. A polypeptide is made using synthetic mRNA molecules as shown.
Synthetic mRNA used
Polypeptide produced
UUUAAAUUUAAA
Phenylalanine-Iysine-phenylalanine-Iysine

What are the DNA codes for the amino acids phenylalanine and lysine?

S.no
Phenylalanine
Lysine
(a)
AAA
TTT
(b)
AAA
UUU
(c)
GGG
CCC
(d)
TTT
GGG
Explain- Restriction enzymes.
  1. What are the three options that can be thought of, to increase food production?
  2. Mention the reasons for the success of Green Revolution in increasing food production.
  3. Why do we still search for other alternatives to increase food production?
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A technique known as amniocentesis is used to determine fetal abnormalities. This test chromosomal pattern in amniotic fluid. However, this technique is legally banned now.

  1. Identify X and Y in the above given figure.
S. No
X
Y
(a)
Amnion
Chorion
(b)
Uterine wall
Placenta
(c)
Placenta
Uterine wall
(d)
Uterine wall
Amnion
  1. What is the function of Z?
  1. Z is an amniotic fluid which prevents dessication of an embryo.
  2. Z is yolk sac which functions as site of early blood cell formation.
  3. Z is amnion, which takes part in placenta formation.
  4. None of these
  1. Which of the following diseases can not be diagnosed by amniocentesis?
  1. Down's syndrome.
  2. Sickle cell disease.
  3. Jaundice.
  4. Cystic fibrosis.
  1. Assertion: Amniocentesis is legally banned for sex determination.

Reason: Amniocentesis was being misused for aborting normal female fetus.

  1. Both assertion and reason are true, and reason is the correct explanation of assertion.
  2. Both assertion and reason are true, but reason is not the correct explanation of assertion.
  3. Assertion is true, but reason is false.
  4. Both assertion and reason are false.
  1. Which of these is a non-invasive technique of detecting fetal disorder?
  1. Fetoscopy.
  2. Chorionic villi sampling.
  3. Amniocentesis.
  4. Ultrasound imaging.