Question
How does a chromosomal disorder differ from a Mendelian disorder?
✓
Answer
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S. No.
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Mendelian disorder
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Chromosomal disorder
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(i)
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This disorder is mainly due to alteration or mutation in the single gene.
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This disorder is caused due to absence or excess or abnormal arrangement of one or more chromosomes.
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(ii)
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This follows Mendel’s principles of inheritance.
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This does not follow Mendel’s principles ofinheritance.
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(iii)
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This may be recessive or dominant in nature.
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This is always dominant in nature.
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(iv)
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For example, haemophilia, sickle–cell anaemia.
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For example, Turner’s syndrome.
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