Question
How is early detection of infectious diseases possible by molecular diagnosis?
✓
Answer
Molecular diagnostics:
- Low concentration of viral or bacterial DNA in a host body can be detected (much before the symptoms of the disease appear) by polymerase chain reaction amplification).
- Clones of genes can be used as probes to detect the presence of complementary (normal) strands of DNA in a mutant-clone, hybridisation does not occur and hence, the radioactivity does not appear in the autoradiography) photographic films.
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