MCQ
In aerobic respiration, first CO2 is liberated during:
- AOxidation of pyruvate
- BDecarboxylation of oxalosuccinate
- CDecarboxylation of α-ketoglutarate
- DAlcoholic fermentation
✓
Answer
- Oxidation of pyruvate
Explanation:
The pyruvic acid generated in the glycolysis enters into the mitochondrial matrix, undergoes oxidative decarboxylation and forms active acetate in a coordinated series of reactions catalyzed by the multienzyme complex.
The reaction requires the participation of an enzyme pyruvate dehydrogenase and several coenzymes including NAD+, coenzyme A, thiamine pyrophosphate and lipoic acid.
The above reaction involves the conversion of pyruvic acid to acetyl coenzyme A followed by the release of the first molecule of carbon dioxide.
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