MCQ
In gene therapy, DNA is inserted into a cell to compensate for:
- AMutant alleles
- BAbsence of plasmids
- CLack of copy DNA
- DNone of the above
Explanation:
Gene therapy can be used to add the external DNA to the genome to replace a missing gene product, gene targeting to correct mutant alleles or to treat dominantly acting diseases via antisense RNA expression or the expression of intracellular antibodies. If the mutated gene makes a faulty protein or no protein, gene therapy introduces a normal copy of the gene, via a vector, to restore the function of the gene to produce a functional protein.
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Reason : $m-RNA$ is transferred from the nucleus into the cytoplasm where ribosomes and amino acids are available for protein synthesis.