MCQ
In the extrinsic clotting pathway, the active factor VII activates which factors?
- AX and XI
- BIX and XI
- CIX and X
- DXI and XII
Explanation:
When there is damage to the blood vessel, the factor VII leaves the circulation and comes in contact with the tissue factor (TF), which is expressed on tissue-factor bearing cells, forming an activated TF - FVIIa. This TF - FVIIa activates factor IX and factor X.
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