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Principles of Inheritance and Variation — BIOLOGY STD 12 Science — Question

Maharashtra BoardEnglish MediumSTD 12 ScienceBIOLOGYPrinciples of Inheritance and Variation1 Mark
MCQ
Phenylketonuria $\text{(PKU)}$ is an inherited disease which refers to:
  • A
    Decrease in phenylalanine in tissue and blood
  • ✓
    Increase in phenyl pyruvic acid in tissue and blood
  • C
    Elimination of sugar in urine
  • D
    Elimination of gentisic acid in urine
✓

Answer

Correct option: B.
Increase in phenyl pyruvic acid in tissue and blood
Phenylketonuria is the genetically inherited disease.It occurs due to deficiency of an enzyme phenylalanine hydroxylase which catalyses the conversion of amino acid phenylalanine into tyrosin.This results in the increased level of phenylalanine in the blood at the same time it starts depositing in various body tissue.

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