Principles of Inheritance and Variation — BIOLOGY STD 12 Science — Question

Explain the inheritance of hemophilia?

Insulin in the human body is secreted by pancreas as prohormone/ proinsulin. The schematic polypetide structure of proinsulin is given below. This proinsulin needs to undergo processing before it becomes functional in the body. Answer the questions that follow:

1. State the change the proinsulin undegoes at the time of its processing to become functional.
2. Name the technique the American company Eli Lilly used for the commercial production of human insulin.
3. How are the two polypeptides of a functional insulin chemically held together?

Mention the role of the following in E.coli cloning vector pBR 322.

1. Selectable marker.
2. ori.
3. rop.

Answer the following questions:
Why is tender coconut considered a healthy source of nutrition?

Name and describe any three causes of biodiversity losses.

Name two hormones that are constituents of contraceptive pills. Why do they have high and effective contraceptive value? Name a commonly prescribed non – steroidal oral pill.

Why are menstrual cycles absent during pregnancy.

Why are the males of Grasshoper and Drosophila said to show heterogamete? Explain female heterogamete with the help of an example.

Write the causes and symptoms of pheny ketonuria and sickle cell anemia.

Both Haemophilia and Thalassemia are blood related disorders in humans. Write their causes and the difference between the two. Name the category of genetic disorder they both come under.