MCQ
Study the given pedigree chart. Find out the inheritance pattern of disease.

  • A
    Inheritance of a sex-linked inborn error of metabolism like phenylketonuria.
  • B
    Inheritance of a condition like phenylketonuria as an autosomal recessive trait.
  • C
    The pedigree chart is wrong as this is not possible.
  • D
    Inheritance of an autosomal dominant disease like Huntington disease.

Answer

  1. Inheritance of a condition like phenylketonuria as an autosomal recessive trait.

Explanation:

The pedigree chart shows the inheritance of an autosomal recessive trait, as children of normal parents are affected.

This is possible only in the case of a recessive inheritance because both parents are carriers of the disease.

Apart from that, both male child and female child are affected in second-generation so there are higher chances that pedigree belongs to an autosomal inheritance.

An example of an autosomal recessive trait is phenylketonuria.

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