MCQ
Temin worked on which of the following virus?
- ARhinovirus
- BDengue virus
- CHerpes virus
- DRetrovirus
Explanation:
H. Temin and D. Baltimore showed that the retroviruses namely Rous sarcoma virus and the AIDS virus can make an RNA-dependent DNA polymerase that synthesizes a DNA copy (cDNA) of viral RNA.
The cDNA is made into double stranded molecule which is integrated into host genome where it is replicated and transcribed with host DNA; the topsy curvy path of flow of genetic information, i.e., RNA-DNA-RNA-protein.
The enzyme was termed as reverse transcriptase. Rhinovirus, dengue virus and herpes viruses are not retroviruses and follow the linear path of flow of genetic information DNA-RNA-protein.
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