MCQ
The most striking example of point mutation is found in a disease is called as:
- ANight blindness
- BThalassemia
- CDown's syndrome
- DSickle-cell anaemia
Explanation:
A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base substitution, insertion, or deletion of the genetic material, DNA or RNA.
Sickle-cell anemia is caused by a point mutation in the β-globin chain of hemoglobin, causing the hydrophilic amino acid glutamic acid to be replaced with the hydrophobic amino acid valine at the sixth position.
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