MCQ
The oxygen $–$ haemoglobin dissociation curve will show a right shift in case of:
  • High $\ce{pCO_2}$
  • B
    High $\ce{pO_2}$.
  • C
    Low $\ce{pO_2}$
  • D
    Less $\ce{ H^+}$ concentration.

Answer

Correct option: A.
High $\ce{pCO_2}$
The oxygen haemoglobin dissocia$-$tion curve is shifted either to right or left by various factors. The shift of curve to right indicates dissociation of oxygen from haemoglobin. It occurs in the following conditions :
  1. Decrease in partial pressure of oxygen.
  2. Increase in partial pressure of carbon dioxide $($Bohr Effect$)$.
  3. Increase in hydrogen ion concentration and decrease in $\ce{pH} ($acidity$)$.
  4. Increased body temperature.
  5. Excess of $2, 3-$diphosphoglycerate $\text{(DPG)}$.

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