MCQ
The $p{K_a}$ of acetylsalicylic acid (aspirin) is $3.5$ . The $pH$ of gastric juice in human stomach is about $2-3 $ and the $pH$ in the small intestine is about $8. $ Aspirin will be
  • A
    Unionized in the small intestine and in the stomach
  • B
    Completely ionized in the small intestine and in the stomach
  • C
    Ionized in the stomach and almost unionized in the small intestine
  • Ionized in the small intestine and almost unionized in the stomach

Answer

Correct option: D.
Ionized in the small intestine and almost unionized in the stomach
(d) Aspirin is a weak acid. Due to common ion effect it is unionised in acid medium but completely ionised in alkaline medium.

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