$Hb{O_2} + {H_3}{O^ + }C{O_2} \rightleftharpoons \left( {{H^ + } - Hb - C{O_2}} \right) + {O_2} + {H_2}O$
Release of $O_2$ is favoured when there is
$(A)$ Nucleotide form from nucleoside and phosphate group by ether linkage
$(B)$ In nucleoside, nitrogenous base link with hexose sugar of $DNA$ or $RNA$
$(C)$ $DNA$ and $RNA$ are differ in only nature of sugar
$(D)$ $A = T$ and $C \equiv G$ are hydrogen bond between nitrogenous base