MCQ
Two statements are given-one labelled Assertion and the other labelled Reason. Select the correct answer to these questions from the codes $(a), (b), (c)$ and $(d)$ as given below.
Assertion: $\text{YAC}$ vectors have been exploited extensively in the mapping of large genomes.
Reason: $\text{YAC}$ vectors have a composite structure made of bacteriophage and plasmid.
  • A
    Both assertion and reason are true and reason is the correct explanation of assertion.
  • B
    Both assertion and reason are true but reason is not the correct explanation of assertion.
  • Assertion is true but reason is false.
  • D
    Both assertion and reason are false.

Answer

Correct option: C.
Assertion is true but reason is false.
Yeast Artificial Chromosome $\text{(YACs)}$ is a human engineered $\text{DNA}$ molecule derived from the yeast. $\text{YACs}$ are often used in connection with mapping and sequencing of genomes. Segments of an organism's $\text{DNA}$, upto one million base pairs in length, can be inserted into $\text{YACs}$. The $\text{YACs}$ are then taken up by yeast cells. As the yeast cell grow and divide, they amplify the $\text{YAC}$ $\text{DNA}$, which can be isolated and used for $\text{DNA}$ mapping and sequencing.

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