Question
What are the main causes of cancer?

Answer

Causes of Cancer : Following carcinogenic factors are responsible for causing cancer.
  1. Chemicals : Many induce development of cancer. E.g. nicotine, caffeine, polycyclic hydrocarbons and products of combustion of coal and oil. Sex hormone and steroids, if given or secreted in excess, can cause cancer. E.g. Breast cancer.
  2. Radiation : Radiations such as X-rays, gamma-rays, cosmic rays, ultra-violet rays are carcinogenic.
  3. Viruses : Virus possessing oncogenes (v-onc genes) are carcinogenic. E.g. EBV (Epstein-barr virus), HPV (Human papiloma virus) are oncogenic viruses.
  4. Oncogenes : Cellular oncogenes (c-onc genes) or proto-oncogenes can cause cancer. They are present in normal cells but if activated they lead to oncogenic transformation of cells.
  5. Addiction : Addictive substances like cigarette smoke, tobacco lead to cancer of mouth, lips and lungs. Alcohol can cause cancer of oesophagus, stomach, intestine and liver. Drugs like marijuana or anaerobic steroids can also cause cancer.

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