Question
What makes carbon monoxide more harmful to animals than carbon dioxide?

Answer

Haemoglobin consists of a protein globin and pigment haem. The four portions of iron in haem combine with molecule of oxygen. It is an easy reversible reaction to form oxyhaemoglobin.
$\text{Hb}+\text{O}_2\rightleftharpoons\text{HbO}_2$
Whereas, the complex formed by the reaction of carbon monoxide and haemoglobin is incredibly strong:
$\begin{matrix}\text{Hb}+\text{CO}\xrightarrow{\ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ \ }\text{HbCO}\\^\text{(Haemoglobin)}\ ^\text{(Carboxy haemoglobin)}\end{matrix}$
As a result of this strong bonding between the haemoglobin and carbon monoxide, the haemoglobin looses its affinity to oxygen thus, may lead to choking or even death.

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