MCQ
Which is most reactive of the following
- AEthyl acetate
- BAcetic anhydride
- CAcetamide
- ✓Acetyl chloride
✓
Answer
Correct option: D.
Acetyl chloride
d
(d) The order of reactivity of acid derivatives towards different reactions decreases in the order,
(d) The order of reactivity of acid derivatives towards different reactions decreases in the order,
$RCOCl > {(RCO)_2}O > RCOOR' > RCON{H_2}$
In other words, the reactivity decreases as the basicity of the leaving group increases i.e.,
$C{l^ - } < RCO{O^ - } < R{O^ - } < NH_2^ - $
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