MCQ
Which one is the cofactor for the proteolytic enzyme carboxypeptidase?
  • A
    Mercury
  • B
    Copper
  • C
    Zinc
  • D
    Magnesium

Answer

(c) Zinc
Explanation: Zinc is a cofactor for the proteolytic enzyme carboxypeptidase and forms coordination bonds with the side chains of two histidines and one glutamic acid residue at the active site. A fourth bond is formed between zinc and the a- carboxyl group of the substrate amino acids, and it is here that the cleavage of the peptide occurs.

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