MCQ
Which one of the following is a base analogue?
  • A
    Nitrous acid
  • B
    Colchicine
  • $5 -$ bromouracil
  • D
    Caffeine

Answer

Correct option: C.
$5 -$ bromouracil
$5 -$ bromouracil is a brominated derivative of uracil that acts as an antimetabolite or base analog, substituting for thymine in $\text{DNA},$ can induce $\text{DNA}$ mutation in the same way as $2-$aminopurine. It is used mainly as an experimental mutagen.

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