Gujarat BoardEnglish MediumSTD 12 ScienceBIOLOGYMolecular Basis of Inheritance1 Mark
MCQ
Which one of the following is a base analogue?
A
Nitrous acid
B
Colchicine
✓
$5 -$ bromouracil
D
Caffeine
✓
Answer
Correct option: C.
$5 -$ bromouracil
$5 -$ bromouracil is a brominated derivative of uracil that acts as an antimetabolite or base analog, substituting for thymine in $\text{DNA},$ can induce $\text{DNA}$ mutation in the same way as $2-$aminopurine. It is used mainly as an experimental mutagen.
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