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Molecular Basis of Inheritance — BIOLOGY STD 12 Science — Question

Rajasthan BoardEnglish MediumSTD 12 ScienceBIOLOGYMolecular Basis of Inheritance1 Mark
MCQ
Which scientist gave wobble hypothesis?
  • A
    R. W. Holley
  • B
    H. G. Khorana
  • C
    M. Nirenberg
  • D
    F. H. C. Crick
✓

Answer

  1. F. H. C. Crick

Explanation:

Crick (1966) proposed the wobble hypothesis, in order to solve apparent dilemma. According to this hypothesis, only the first two bases of the codon have a precise pairing with the bases of the anticodon of mRNA, while the pairing between the third bases of codon and anticodon may wobble.

Wobble pairing

Anticod on 
(first base)
Cod on 
(third base)
U
A, G
C
G
A
U
G
U, C
I(inosine, resemles G)
U, C, A

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