Why does a patient of ADA-deficiency require repeated infusion of… - Vidyadip

Question

Why does a patient of ADA-deficiency require repeated infusion of genetically engineered lymphocytes? Suggest a possible permanent remedy.

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Answer

The genetically- engineered lymphocytes have a life span; hence the patient requires periodic infusion of genetically engineered lymphocytes and the cure is not permanent.
There could be a permanent cure if the gene isolated from marrow cells producing ADA is introduced into the cells at early embryonic stages.

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