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Biotechnology: Principles and Processes — BIOLOGY STD 12 Science — Question

Maharashtra BoardEnglish MediumSTD 12 ScienceBIOLOGYBiotechnology: Principles and Processes2 Marks
Question
Why is the introduction of genetically engineered lymphocytes into an ADA deficiency patient not a permanent cure? Suggest a possible permanent cure.
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Answer

Lymphocytes not immortal/short lived, hence patient requires periodic infusion of such genetically engineered lymphocytes, however if a gene producing ADA is isolated from marrow cells, and introduced into the cells at early embryonic stages it could be a permanent cure.

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