Addison’s disease is caused due to hyposecretion of glucocorticoids and mineralocorticoids from the adrenal cortex. Muscular weakness, low BP, loss of appetite, vomiting, hyperpigmentation of the skin, low metabolic rate, subnormal temperature, reduced blood volume – weight loss are the symptoms that occur in Addison’s disease. Reduces aldosterone secretion increases urinary excretion of Na Cl. and decreases potassium excretion leading to dehydration.