Question
Write short notes :
Acetylation
Acetylation
✓
Answer
Acetylation : Aliphatic and aromatic primary and secondary amines react with acid chloride and acid anhydride by nucleophilic substitution reaction. This reaction is known as acylation.
This reaction is considered as the replacement of hydrogen atom of $- NH _2$ or $> N - H$ group by aelyl group. when $CH _3 COCl$ is taken in this reaction then it is called acetylation. This reaction is performed in presence of pyridine which are moves HCl so formed shifts equilibrium to the right hand side.
When amines are treated with benzoyl chloride then this reaction is called benzyoylation and on the basis of name of scientist this is called Schotten-Baumann reaction.
Amines reacts wih carboxylic acids at room temperature forms salts.
This reaction is considered as the replacement of hydrogen atom of $- NH _2$ or $> N - H$ group by aelyl group. when $CH _3 COCl$ is taken in this reaction then it is called acetylation. This reaction is performed in presence of pyridine which are moves HCl so formed shifts equilibrium to the right hand side.
When amines are treated with benzoyl chloride then this reaction is called benzyoylation and on the basis of name of scientist this is called Schotten-Baumann reaction.
Amines reacts wih carboxylic acids at room temperature forms salts.
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