Amino acids can be classified as $\alpha-, \beta-, \delta-,$and so on depending upon the relative position of amino group with respect to carboxyl group. Which type of amino acids form polypetide chain in proteins?
Vitamin C are soluble in water. Water soluble vitamins must be supplied regularly in diet because they are readily excreted in urine and cannot be stored in our body.
How do you explain the presence of five —OH groups in glucose molecule?
Answer
Glucose gives penta-acetyl derivative on acetylation with acetic anhydride. $\text{CHO}| (\text{CHOH})_4|\text{CH}_2\text{OH}|\text{CH}_2\text{OH}\xrightarrow{\ \ \ \ \ \ \ \ \ }\text{CHO}|(\text{CHOCOCH}_3)_4|\text{CH}_2\text{OH}_2\text{OCOCH}_3$ This confirms the presence of five -OH groups.
Monosaccharides contain carbonyl group hence are classified, as aldose or ketose. The number of carbon atoms present in the monosaccharide molecule are also considered for classification. In which class of monosaccharide will you place fructose?
Answer
Monosaccharides contain carbonyl group. Hence, are classified as aldose or ketose. When aldehyde group is present, the monosaccharides are known as aldose. When ketone group is present, the monosaccharides are known as ketose. Fructose has molecular formula C6H12O6 containing six carbon and keto group and is classified as ketohexose.
The letters ‘D’ or ‘L’ before the name of a stereoisomer of a compound indicate the correlation of configuration of that particular stereoisomer. This refers to their relation with one of the isomers of glyceraldehyde. Predict whether the following compound has ‘D’ or ‘L’ configuration.
Answer
The letters ‘D’ or ‘L’ before the name of any compound indicate the relative configuration of a particular stereoisomer. This refers to their relation with a particular isomer of glyceraldehydes. D’ before the name of glucose represents the configuration whereas ‘(+)’ represents dextrorotatory nature of the molecule. It may be remembered that ‘D’ and ‘L’ have no relation with the optical activity of the compound. For assigning the configuration of monosaccharides, it is the lowest asymmetric carbon atom which is compared. The given compound has L-configuration.
In nucleoside a base is attached at 1′ position of sugar moiety. Nucleotide is formed by linking of phosphoric acid unit to the sugar unit of nucleoside. At which position of sugar unit is the phosphoric acid linked in a nucleoside to give a nucleotide?
Answer
Phosphoric acid unit is linked preferably at 5′-position of sugar moiety of a nucleoside to give a nucleotide.
Why does compound (A) given below not form an oxime?
Answer
Glucose pentaacetate (structure A) doesn’t have a free —OH group at C1 and so can’t be converted to the open chain form to give —CHO group and hence doesn’t form the oxime.
Some enzymes are named after the reaction, where they are used. What name is given to the class of enzymes which catalyse the oxidation of one substrate with simultaneous reduction of another substrate?
Answer
Oxidoreductase is class of enzymes which catalyse the oxidation of one substrate with simultaneous reduction of another substrate.
Which moieties of nucleosides are involved in the formation of phosphodiester linkages present in dinucleotides? What does the word diester in the name of linkage indicate? Which acid is involved in the formation of this linkage?
Activation energy for the acid catalysed hydrolysis of sucrose is 6.22kJ mol–1, while the activation energy is only 2.15kJ mol–1 when hydrolysis is catalysed by the enzyme sucrase. Explain.
Answer
Enzymes are biocatalysts. They reduce the magnitude of activation energy by providing alternative path. In the hydrolysis of sucrose, the enzyme sucrase reduces the activation energy from 6.22kJ mol-1 to 2.15kJ mol-1. As a result, enzyme catalysed reactions occur at a much faster rate than the ordinary chemical reactions using conventional catalysts.
$\alpha-$Helix is a secondary structure of proteins formed by twisting of polypeptide chain into right handed screw like structures. Which type of interactions are responsible for making the $\alpha-$helix structure stable?
Answer
In $\alpha-$helix, apolypeptide chain is stabilized by the formation of hydrogen bonds between NH— group of amino acids in one turn with the >C —O groups of amino acids belonging to adjacent turn.