Question 14 Marks
Read the following text carefully and answer the questions that follow:
Transgenic animals can serve as factories that in some cases, may produce large amounts of proteins more efficiently. Transgenic mice have been engineered to express human antibodies by introducing a large segment of human DNA encoding human immunoglobulin genes. In transgenic large animals such as cows or sheep proteins of pharmaceutical value can be produced in large quantities in milk which is later purified. Transgenes can be used to alter many phenotypic properties including growth rate, fat composition, milk production, hair texture, etc.
i. In transgenic animals, i.e. cow and sheep proteins of pharmaceutical value are produced in large quantities in which gland. (1)
ii. Why is mouse the most preferred animal for studies on gene transfer? (1)
iii. Why does the production of transgenic animals take place? (2)
OR
Assertion (A): Transgenic mice have been engineered to express human antibodies. (2)
Reason (R): Large segments of human DNA encoding human immunoglobulin have been transferred to mice.
a. Both A and R are true and R is the correct explanation of A.
b. Both A and R are true but R is not the correct explanation of A.
c. A is true but R is false.
d. A is false but R is true.
Transgenic animals can serve as factories that in some cases, may produce large amounts of proteins more efficiently. Transgenic mice have been engineered to express human antibodies by introducing a large segment of human DNA encoding human immunoglobulin genes. In transgenic large animals such as cows or sheep proteins of pharmaceutical value can be produced in large quantities in milk which is later purified. Transgenes can be used to alter many phenotypic properties including growth rate, fat composition, milk production, hair texture, etc.
i. In transgenic animals, i.e. cow and sheep proteins of pharmaceutical value are produced in large quantities in which gland. (1)
ii. Why is mouse the most preferred animal for studies on gene transfer? (1)
iii. Why does the production of transgenic animals take place? (2)
OR
Assertion (A): Transgenic mice have been engineered to express human antibodies. (2)
Reason (R): Large segments of human DNA encoding human immunoglobulin have been transferred to mice.
a. Both A and R are true and R is the correct explanation of A.
b. Both A and R are true but R is not the correct explanation of A.
c. A is true but R is false.
d. A is false but R is true.
Answer
View full question & answer→i. Mammary gland
ii. Short oestrus cycle.
iii. a. All of these Identification and separation of desired gene.
b. Combining the desired gene with appropriate vector.
c. Introduction of vector in cells, tissues or embryos.
OR
(a) Both A and R are true and R is the correct explanation of A.
ii. Short oestrus cycle.
iii. a. All of these Identification and separation of desired gene.
b. Combining the desired gene with appropriate vector.
c. Introduction of vector in cells, tissues or embryos.
OR
(a) Both A and R are true and R is the correct explanation of A.
