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Question 13 Marks
How do you prepare $p-$bromoaniline and $o-$bromoaniline from aniline? Explain.
Answer
Due to the high reactivity of aniline towards electrophilic substitution reaction, substitution occurs at both the $o-$ and $p-$ positions.
Therefore, to make a single substituted derivative of aniline, it is first protected by acetylation to reduce the activation effect of the $- \ce{NH2}$ group.
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Question 23 Marks
Write the reaction of methyl amine with the following :
(i) $HAuCl _4$
(ii) $H _2 PtCl _6$
(iii) $CH _3 COCl$
(iv) $C _6 H _5 COCl$
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Question 33 Marks
Write the equations of the reactions of forming primary amines by the following methods:
(a) Hydrolysis of alkyl isocyanide
(b) Reductive amination of carbonyl compounds
(c) Alkaline hydrolysis of alkyl isocyanate
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Question 43 Marks
Give equations required for the following changes:
(i) Ethanal to methanamine
(ii) Ethanocyl chloride to methanamine
(iii) Ethanoic acid to propan-1-amine.
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Question 53 Marks
Write short notes :
Gabriel phthalimide synthesis.
Answer
Gabriel phthalimide synthesis : This is best method of the preparation of aliphatic amine. In this method phthalimide is treated with ethanolic potassium hydroxide forms potassium sort of phthalimide which on heating with alkyl halide followed by alkaline hydrolysis produces the corresponding primary amine aromatic primary amines like aniline can not be prepared easily by this method because the reactivity of aryl halides is less than alkyl halides.
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Question 63 Marks
Write short notes :
Coupling reaction
Answer
Coupling Reaction : Benzene diazonium chloride reacts with phenol in which the phenol molecule at its pure position is coupled with the diazonium salt to form p-hydroxyazobenzene. This type of reaction is known as coupling reaction. Similarly the reaction of diazonium salt with aniline yields p-aminoazobenzene. This is an example if electrophilic substitution reaction products obtained are coloured and these are azo dyes.
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