Question
A patient is suffering from ADA deficiency. Can he be cured? How?

Answer

A person suffering from ADA deficiency can be cured by various methods which are discusses below:
  • Bone Marrow Transplantation: This is a costly and risky surgical procedure. It requires a suitable donor which is difficult to find. An identical twin is supposed to be the best donor; because chances of tissue rejection are very high in bone marrow transplantation.
  • Enzyme Replacement Therapy: Enzyme replacement therapy is based on administering the missing enzyme to the patient by injection. This involves recurrent treatment that has escalated the cost this therapy.
  • Gene Therapy: Gene therapy involves taking out the lymphocytes from the patient’s blood. Then are lymphocytes are genetically engineered to add the missing gene. Recombinant lymphocytes are grown in suitable medium and then administered to the patient. This too is not a permanent cure because lymphocytes have a certain lifespan. The patient needs to be administered lymphocytes after frequent intervals. However, the gene isolated from marrow cells producing ADA is introduced into cells at early embryonic stage could be permanent cure for this disease.

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A desert lizard (an ectotherm) and a mouse (an endotherm) are placed inside a chamber at 15ºC and their body temperature [T(L) for the lizard and T(M) for the mouse] and metabolic rates [M(L) for lizard and M(M) for the mouse] are monitored.

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Based on the above information, answer the following questions.

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S no.
Reema
Jai
Ankit
(a)
Diabetes
Grave's disease
Rheumatic fever
(b)
Pernicious anaemia
Multiple sclerosis
Myasthenia gravis
(c)
Addison's disease
Rheumatoid arthritis
Hashismoto's thyroiditis
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Systemic lupus erythematosus
Severe combined immunodeficiency disease
AIDS
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Biosphere reserves are multipurpose protected areas which are meant for preserving genetic diversity in representative ecosystems of various natural biomes and unique biological communities by protecting wild populations, traditional life style of tribals and domesticated plant/animal genetic resources. Each biosphere reserve has three zones-core, buffer and transition zone.

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Image
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Oogenesis is the process of formation of ovum in ovaries. It consists of three phases : multiplication, growth and maturation. Oogenesis is controlled by hormones GnRH, LH, FSH. GnRH secreted by the hypothalamus stimulates the anterior lobe of pituitary gland to secrete LH and FSH.

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  4. It causes ovulation.
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  2. Stimulates corpus luteum to secrete progesterone.
  3. Stimulates estrogen formation.
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  1. (A) and (B) only.
  2. (B) and (C) only.
  3. (A), (C) and (D) only.
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  2. Pollen.
  3. Nutrients.
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S. No
P
Q
R
(a)
Geitonogamy
Xenogamy
Autogamy
(b)
Allogamy
Chasmogamy
Cleistogamy
(c)
Autogamy
Geitonogamy
Xenogamy
(d)
Geitonogamy
Allogamy
Autogamy
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  2. Cleistogamy.
  3. Geitonogamy.
  4. Xenogamy.
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  1. P.
  2. Q.
  3. R.
  4. All of these.