Question
A single base mutation in a gene may not ‘always’ result in loss or gain of function. Do you think the statement is correct? Defend your answer.
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Answer
A single base mutation in a gene may not always results in loss or gain of function. We know that a codon is composed of three nucleotides. In simple terms, a codon can be taken as a word which is composed of 3 letters. For making any meaningful sentence we need a complete word. Addition or deletion of a single letter may not result in a meaningful word. Hence, in most of the cases, there is a need of mutation in three bases to affect loss or gain of function. This can be illustrated by following example of a sentence being altered:
- RAM HAS RED CAP.
- RAM HAS BRE DCA P.
- RAM HAS BIR EDC AP.
- RAM HAS BIG RED CAP.
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