Amount of DNA content (C) per cell During anaphase II of the meiotic cycle, the chromatids separate as a result of the splitting of the centromere. It is the centromere that holds together the sister chromatids of each chromosome. As a result, the chromatids move toward their respective poles. Therefore, at each pole, a haploid number of chromosomes and a haploid amount of DNA are present. During mitosis, the number of chromosomes remains the same. The DNA duplicated in the S phase gets separated in the two daughter cells during anaphase. As a result, the DNA content (C) of the two newly-formed daughter cells remains the same.