Question
Describe the events taking place during interphase.

Answer

The interphase is divided into three further phases:
  1. G1 phase (Gap 1): The G1 phase corresponds to the interval between mitosis and initiation of DNA replication. During the G1 phase, the cell is metabolically active and continuously grows but does not replicate its DNA. The cells which divide frequently have a shorter Gphase, whereas the cells which divide infrequently have a longer G1 phase.
  2. S phase (Synthesis): The S or synthesis phase marks the period during which DNA synthesis or replication takes place. During this time, the amount of DNA per cell doubles. If the initial amount of DNA is denoted as 2C, then it increases to 4C. However, there is no increase in the chromosome number. If the cell had diploid or 2n number of chromosomes at G1, even after the S phase, the number of chromosomes remains the same, i.e. 2n. The S phase in most eukaryotic cells lasts for 6 to 8 hours. When the S phase begins, the cell must undergo mitosis.
  3. G2 phase (Gap 2): In animal cells, during the S phase, DNA replication begins in the nucleus, and the centriole duplicates in the cytoplasm. During the G2 phase, proteins are synthesised in preparation for mitosis while cell growth continues. The Gphase in most cells lasts for 2 to 5 hours. Some proteins formed in G2 phase cause condensation of chromosomes to initiate mitosis.

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