Question
Differentiate between the following:
Eosinophil and Basophil

Answer

EOSINOPHILBASOPHIL
These cells have bilobed nucleus, where each lobe
is connected by a thin strand.
A basophil has two or more lobes in the nucleus.
The cytoplasmic granules stain orange-red with
acid dyes (eosin). Because of this affinity for
acidic dyes, they are also called acidophils.
Basophil has an affinity for basic dyes and stains blue-black with them.
Their normal count is 60-300 per ml. of blood,
about 2 to 5% of the total WBCs count.
Their number ranges from 35 to 100 per ml of blood, about 0.5 to 1% of the total WBC count.
Increase in the number of eosinophils in blood is
called eosinophilia. It is mainly due to parasitic
infection.
It produces a chemical (histamine) which dilates blood vessels making their wall leaky for other leucocytes to fight germs.
Eosinophils engulf particles formed by antigen-
antibody reaction.
t prevents clotting of blood in the blood vessels, and seratonins, which constrict blood vessels.

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