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Molecular Basis of Inheritance — BIOLOGY STD 12 Science — Question

Rajasthan BoardEnglish MediumSTD 12 ScienceBIOLOGYMolecular Basis of Inheritance1 Mark
Question
How is a polypeptide chain synthesis terminated during protein synthesis?
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Answer

Synthesis of polypeptide chain terminates when a nonsense codon of mRNA reaches the A-site. There are three nonesense codon UAA, UAG and UGA, which are not recognised by any of the tRNAs. Therefore no more amino-acyl tRNA reaches the A site. The P site t-RNA is hydrolysed and the completed polypeptide is released in the presence of GTP dependent release factor.

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