a Griffith $(1928)$ described the phenomenon of bacterial transformation. He experimented with the smooth and rough strains of Streptococcus pneumoniae. Smooth strains of bacteria were virulent or pathogenic $\&$ cause pneumonia.
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$A$ : Polypeptide sequences are dictated by $DNA$ and represented by $mRNA$.
$R$ : Sequence of amino acids in a polypeptide can be predicted by the exact sequence of nucleotides on the $mRNA$ and template $DNA$