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Body Fluids and Circulation — BIOLOGY STD 11 Science — Question

Gujarat BoardEnglish MediumSTD 11 ScienceBIOLOGYBody Fluids and Circulation1 Mark
MCQ
In the extrinsic clotting pathway, the active factor $VII$ activates which factors?
  • A
    $X$ and $XI$
  • B
    $IX$ and $XI$
  • ✓
    $IX$ and $X$
  • D
    $XI$ and $XII$
✓

Answer

Correct option: C.
$IX$ and $X$
When there is damage to the blood vessel, the factor $VII$ leaves the circulation and comes in contact with the tissue factor $(TF),$ which is expressed on tissue$-$factor bearing cells, forming an activated $\text{TF - FVIIa}$. This $\text{TF - FVIIa}$ activates factor $IX$ and factor $X$.

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