Question
Monocistronic structural genes in eukaryotes have interrupted coding sequences. Explain. How are they different in prokaryotes?
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Answer
- In eukaryotes, the hnRNA (primary transcript of mRNA) has coding sequences, called exons as well as non-coding sequences, called introns, i.e. the information is split.
- It undergoes a process, called splicing, in which the introns are removed and the exons are joined together in a particular manner, to form the functional mRNA.
- In prokaryotes, the mRNA is polycistronic, i.e. codes for more than one polypeptide.
- The information is continuous and no splicing is required.
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