Question
Myosin filament

Answer

i. Myosin filament:

  1. Each myosin filament is a polymerized protein.
    Many meromyosins (monomeric proteins) constitute one thick filament.
  2. Myosin molecule consists of two heavy chains (heavy meromyosin / HMM) coiled around each other forming a double helix. One end of each of these chains is projected outwardly is known as cross bridge. This end folds to form a globular protein mass called myosin head.
  3. Two light chains are associated with each head forming 4 light chains/light meromyosin / LMM.
  4. Myosin head has a special ATPase activity. It can split ATP to produce energy.
  5. Myosin contributes 55% of muscle proteins.
  6. In sarcomere, myosin tails are arranged to point towards the centre of the sarcomere and the heads point to the sides of the myofilament band.

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