MCQ
Select the incorrect Statement regarding $\text{DNA}$ replication with respect to the template strand :
  • A
    Leading strand is formed in $5 \rightarrow 3$ direction.
  • B
    Okazaki fragments are formed in $5 \rightarrow 3$ direction.
  • $\text{DNA}$polymerase catalyses polymerisation in $5 \rightarrow 3$ direction.
  • D
    $\text{DNA}$ polymerase catalyses palymerisation in $3 \rightarrow 5$ direct

Answer

Correct option: C.
$\text{DNA}$polymerase catalyses polymerisation in $5 \rightarrow 3$ direction.
Since $\text{DNA}$ polymerase requires a free $\text{3' OH}$ group for initiation of synthesis, it can synthesize in only one direction by extending the $3'$ end of the preexisting nucleotide chain.
Hence, $\text{DNA}$ polymerasemoves along the template strand in a $3'–5'$ direction, and the daughter strand is formed in a $5'–3'$ direction.

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